A Large-scale, Randomized Trial of Orbital Atherectomy vs. Conventional Balloon Angioplasty in Severely Calcified Coronary Arteries Prior to DES Implantation: The ECLIPSE Trial

A Large-scale, Randomized Trial of Orbital Atherectomy vs. Conventional Balloon Angioplasty in Severely Calcified Coronary Arteries Prior to DES Implantation: The ECLIPSE Trial

The ECLIPSE trial demonstrated that routine use of orbital atherectomy prior to DES implantation in severe calcified coronary lesions did not improve minimal stent area (MSA) or TVF (cardiac death, target-vessel related myocardial infarction (MI), and ischemia-driven TVR) at one year compared to conventional balloon angioplasty, according to a study presented by Dr. Ajay J. Kirtane, Columbia University Irving Medical Center, USA, in the Late-Breaking Clinical Trials session at TCT 2024.

Between March 2017 and April 2023, 2,005 patients (2,492 lesions) from 104 US hospitals, who had a w...
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