Long-Term Prognostic Implications of Non-Culprit Lesions in Patients Presenting With an Acute Myocardial Infarction: Is It the Angiographic Stenosis Severity or the Underlying High-Risk Morphology?
In patients with acute myocardial infarction (AMI), angiographic ≥50% stenosis in non-culprit lesions and a higher number of thin-cap fibroatheroma (TCFA) detected on OCT were associated with an increased risk of major adverse cardiovascular events (MACE: cardiac death, non-fatal myocardial infarction, and unplanned revascularization). However, the prognostic impact of obstructive lesions appeared to be primarily attributable to the presence of underlying TCFA, Dr. Jiannan Dai and colleagues, The 2nd Affiliated Hospital of Harbin Medical University, China, reported in the April 15 issue of Circulation.
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