Regression and Stabilization of Coronary Atheroma with Lipid-Lowering Therapy: The PACMAN-AMI Trial

Regression and Stabilization of Coronary Atheroma with Lipid-Lowering Therapy: The PACMAN-AMI Trial

According to the PACMAN-AMI trial, one-third of post-AMI patients receiving high-intensity lipid-lowering therapy showed a decrease in atheroma volume, a reduction in maxLCBI4mm, and increase in minimal fibrous capsule thickness, which were associated with treatment with alirocumab, higher baseline lipid content, and fewer cardiovascular events. Dr. Flavio G. Biccire of Bern University Hospital, Switzerland, and colleagues reported in the October 31 issue of the Journal of the American College of Cardiology.

In the PACMAN-AMI trial, 300 AMI patients with LDL-C >125mg/dL without statins or >70mg/dL wit...
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