Left Ventricular Unloading With Impella in High-Risk PCI: The CHIP-BCIS3 Trial

Left Ventricular Unloading With Impella in High-Risk PCI: The CHIP-BCIS3 Trial

The CHIP-BCIS3 trial demonstrated that among patients with severe left ventricular dysfunction undergoing complex PCI, elective left ventricular unloading with Impella during PCI did not reduce a composite of death, stroke, spontaneous MI, cardiovascular hospitalization, or periprocedural myocardial injury compared with PCI without planned mechanical circulatory support, according to a study presented by Dr. Divaka Perera, King’s College London, UK, in the Late-Breaking Clinical Trials session at ACC.26.

In the CHIP-BCIS3 trial, 300 patients enrolled from 21 hospitals in the UK between August 2021 and D...
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