Effect of SGLT2 Inhibitors on Carotid IMT in Patients with Type 2 Diabetes Mellitus: The PROTECT Study

Effect of SGLT2 Inhibitors on Carotid IMT in Patients with Type 2 Diabetes Mellitus: The PROTECT Study

The PROTECT trial showed that treatment with an SGLT2 inhibitor (ipragliflozin) over 24 months did not prevent progression of intima-media complex thickness (IMT) of the carotid artery compared with non-SGLT2 inhibitor treatment in patients with type 2 diabetes. Dr. Atsushi Tanaka, of Saga University, presented at the Late Breaking Clinical Trials session at the 86th Annual Meeting of the Japanese Circulation Society.

In the PROTECT study, 488 patients with type 2 diabetes were enrolled from September 2015 to June 20...
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