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Impact of Guideline-Directed Medical Therapy on 2-Year Mortality in Japanese Patients Undergoing Endovascular Therapy for Femoropopliteal Lesions: LEADers-FP Registry

The LEADers-FP registry demonstrated that guideline-directed medical therapy (GDMT) with three agents—antiplatelet therapy, statins, and renin-angiotensin system (RAS) inhibitors—may reduce the 2-year risk of all-cause mortality, cardiovascular death, and cardio-cerebrovascular death in Japanese patients who underwent endovascular therapy (EVT) for femoropopliteal artery lesions, according to a study presented by Dr. Tatsuro Takei, Tenyoukai Central Hospital, Japan, in the Late Breaking Clinical Trials session of the 89th Annual Scientific Meeting of the Japanese Circulation Society.

This retrospective observational study examined the impact of GDMT on 2-year mortality in 1,756 pati...

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