Individual patient data meta-analysis of paclitaxel-coated balloons vs drug-eluting stents for small-vessel coronary artery disease: The ANDROMEDA study

Individual patient data meta-analysis of paclitaxel-coated balloons vs drug-eluting stents for small-vessel coronary artery disease: The ANDROMEDA study

The ANDROMEDA study demonstrated that in patients with de novo small vessel coronary artery disease, treatment with a paclitaxel-coated balloon (PCB) was associated with a lower 3-year risk of major adverse cardiac events (MACE; all-cause death, MI, target lesion thrombosis, and TVR) compared with drug-eluting stents (DES), while no significant difference was observed in target lesion failure (TLF; cardiac death, MI, and TLR), Dr. Simone Fezzi and colleagues, Verona University Hospital, Italy, reported in the May 1 issue of the European Heart Journal.

The researchers performed a patient-level meta-analysis of three randomized trials (1,154 patients,...
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